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News Children exposed to paracetamol during pregnancy have poor gross motor development

Article in 'News' Written by Arul Prakash Published Oct 27, 2013

  1. children-skills.

    Paracetamol is prescribed and used widely but is it safe to use during pregnancy? Norwegian Mother and Child Cohort study conducted by School of Pharmacy, University of Oslo reveal that children exposed to long-term use of paracetamol during pregnancy had substantially adverse developmental outcomes at 3 years of age.

    Children exposed to prenatal paracetamol for more than 28 days had poorer gross motor development. The largest muscles in our body that help us run, sit or even walk upright are governed by gross motor skills and gross motor development is an key part of a children growing up.

    Researchers used data collected through a period of over 11 years between 1999 and 2008. Pregnant women who were eligible were asked to report their use of paracetamol during various stages of their pregnancy and mothers were asked to fill out a questionnaire after three years since pregnancy. In total data from 48, 631 children were collected and within that sample about 2919 were used for familial and genetic factors.

    Researchers were able analyse communication,gross motor development, behaviour problems, and temperament based on prenatal paracetamol exposure using generalized linear regression, adjusting for a number of factors, including febrile illness, infections and co-medication use during pregnancy.

    Further reading : Prenatal paracetamol exposure and child neurodevelopment: a sibling-controlled cohort study
    agnhild Eek Brandlistuen, Eivind Ystrom, Irena Nulman, Gideon Koren and Hedvig Nordeng1
    • Arul Prakash

      Article by Arul Prakash

      Editor and founder of BiotechCareer.Org. He is an Industrial Biotechnologists and also a web developer, gooner, blogger, and foodie.

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