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News New uses for bisphosphonates in potential biomedical applications

Article in 'News' Written by Arul Prakash Published Nov 21, 2013

  1. Researchers from University of Jyväskylä have discovered the ability of Bisphosphonates to form gels in pure water, which has opened up new uses for the material.

    The study published in the international Journal of Materials Chemistry B: Materials for biology and medicine by research team from Department of Chemistry of University of Jyväskylä revealed this discovery. The research team was interested in the gelation tendencies of these materials and studied the structures in the gel through structural analysis and synthesised the studied materials.

    bisphosphonates-gel.

    Researchers say it has given them insight into factors that affect the gelation process which could have potential biomedical applications. Bisphosphonates are already been used to treat osteoporosis and other bone related issues.

    Forms reversible gels called "Supramolecular" gels

    bisphosponates.
    What makes these Bisphosphonate gels different from normal chemical gels is that these gels are reversible, they change their form depending on stimulus from external source such as heat. When the stimulus is removed the interaction between lower molecular mass compounds increases reforming into a gel.

    This property makes Supramolecular gels ideal for use in materials chemistry and optoelectronics. Furthermore, biomaterials based on supramolecular gels may find use in biomedicine, drug delivery, and regenerative medicine.

    Further reading: First bisphosphonate hydrogelators: potential composers of biocompatible gels
    Alanne, A.-L., Lahtinen, M., Löfman, M., Turhanen, P., Kolehmainen, E., Vepsäläinen, J., Sievänen, E.
    • Arul Prakash

      Article by Arul Prakash

      Editor and founder of BiotechCareer.Org. He is an Industrial Biotechnologists and also a web developer, gooner, blogger, and foodie.

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